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SPACE Collaborative Group, P. A. Ringleb, J. Allenberg, H. Brückmann, H. H. Eckstein, G. Fraedrich, M. Hartmann, M. Hennerici, O. Jansen, G. Klein, A. Kunze, P. Marx, K. Niederkorn, W. Schmiedt, L. Solymosi, R. Stingele, H. Zeumer and W. Hacke, “30 Day Results from the SPACE Trial of Stent-Protected Angioplasty versus Carotid Endarterectomy in Symptomatic Patients: A Ran domized Noninferiority Trial,” Lancet, Vol. 368, No. 9543, 2006, pp. 1239-1247.

has been cited by the following article:

• TITLE: CAS-Complications Rate and Relation to Risk Factors

  AUTHORS: Kamil Zeleňák, Vladimír Nosáľ, Jana Zeleňáková, Egon Kurča, Igor Šinák, Štefan Sivák, Hubert Poláček

  KEYWORDS: CAS; Carotid Artery Stenting; Risk Factors; Elderly Patients; Age

  JOURNAL NAME: Open Journal of Radiology, Vol.3 No.1, March 12, 2013

  ABSTRACT: Purpose: The aim of the study was to evaluate the risk factors for CAS with cerebral protection and the incidence of complication in patients with severe carotid stenosis. Materials and Methods: Overall, 95 consecutive patients with an average age of 64.67 years (28 - 83) (16 women (17%) and 79 men (83%)) were enrolled in the prospective monocentric study. Indication for CAS was symptomatic carotid stenosis ≥70% (n = 60 (63.16%)) or asymptomatic stenosis ≥80% (n = 35 (36.84%)) according to the NASCET criteria on DSA, which were not suitable for surgery. Results: From the selected risk factors, the most frequently found were arterial hypertension in 87 patients (91.6%), ischemic heart disease in 70 (73.7%), hyperlipidemia in 61 (64.2%), history of stroke in 43 (45.3%), diabetes mellitus in 35 (36.8%), smoking in 13 (13.7%), and age more than 75 years in 9 (9.5%). Significantly more frequent complications in elderly patients (more than the age of 75 years) were experienced: TIA (p = 0.049), early death (p = 0.049), restenosis (p = 0.04), and overall mortality (p = 0.04). Conclusion: Among the studied risk factors, only patients more than the age of 75 years were affected by the incidence of serious complications.