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M. Lewin, A. Poujol-Robert, P. Y. Boelle, D. Wendum, E. Lasnier, M. Viallon, J. Guechot, C. Hoeffel, L. Arrive, J. M. Tubiana and R. Poupon, “Diffusion-Weighted Magnetic Resonance Imaging for the Assessment of Fibrosis in Chronic Hepatitis C,” Hepatology, Vol. 46, No. 3, 2007, pp. 658-665. doi:10.1002/hep.21747

has been cited by the following article:

• TITLE: Impact of Field Strength and Respiratory Motion Control on Diffusion-Weighted MR Imaging of the Liver

  AUTHORS: Johanna Berg, Sven Månsson, Jonas Svensson, Olle Ekberg, Markus F. Müller

  KEYWORDS: Magnetic Resonance Imaging; Diffusion; Echo-Planar Imaging; 3 T; Liver; Respiratory Motion

  JOURNAL NAME: Open Journal of Medical Imaging, Vol.3 No.1, March 11, 2013

  ABSTRACT: Purpose: To evaluate the impact of field strength and respiratory motion control on diffusion-weighted MR imaging (DWI) of the liver at 1.5 and 3 T. Material and Methods: Three DWI sequences using seven b-values from 20 - 400 s/mm2 were designed with identical parameters but with different handling of respiratory motion [respiratory triggered (RT), free breathing (FB), breath hold (BH)] on 3 T and 1.5 T. Thirteen volunteers were examined at a 3 T and six of them also at a 1.5 T magnet. DW images were analyzed quantitatively and qualitatively. Regions of interest were placed in cranial, middle and caudal parts of the right liver lobe (RLL) and ADC and SNR were calculated. Results: ADC in RLL tended to be lower at 3 T MRI. Least inter-subject ADC variability was found with RT in the middle RLL at 3 T. Highest ADCs were found caudally in the RLL. Significant differences in ADC between middle and caudal RLL were calculated in FB and RT at 3 T and FB and BH at 1.5 T, respectively. No significant difference in SNR was found between 3 T and 1.5 T. There were significantly more artifacts in the left liver lobe (LLL) compared to the RLL in all sequences and in the LLL at 3 T compared to 1.5 T. Conclusion: Our study suggests that longitudinal hepatic ADC measurements should be performed using equivalent field strength, b-values, and acquisition technique, given influence of these factors on ADC measurements.