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J. A. Paniagua, A. G. de la Sacristana, I. Romero, A. Vidal-Puig, J. M. Latre, E. Sanchez, P. Perez-Martinez, J. Lopez-Miranda and F. Perez-Jimenez, “Monounsaturated Fat-Rich Diet Prevents Central Body Fat Distribution and Decreases Postprandial Adiponectin Expression Induced by a Carbohydrate-Rich Diet in Insulin-Resistant Subjects,” Diabetes Care, Vol. 30, No. 7, 2007, pp. 1717-1723. doi:10.2337/dc06-2220

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• TITLE: A Pilot Clinical Trial on L-Carnitine Supplementation in Combination with Motivation Training: Effects on Weight Management in Healthy Volunteers

  AUTHORS: Satoshi Odo, Koji Tanabe, Masamitsu Yamauchi

  KEYWORDS: L-Carnitine; Weight Management; Motivation Training; Carnipure?

  JOURNAL NAME: Food and Nutrition Sciences, Vol.4 No.2, February 26, 2013

  ABSTRACT: A 4-week low dosage (500 mg/day) L-carnitine supplementation in combination with motivation training was carried out in 24 overweight (BMI 25.8 - 26.6 kg/m2) Japanese males in the course of a double-blind randomized placebo-controlled study. L-carnitine motivated group showed significant body weight loss and a decrement of serum triglyceride level vs. the non-motivated placebo group. Serum adiponectin levels increased in both L-carnitine supplemented groups. The beneficial effects of L-carnitine were amplified by motivation training. For clinical evaluation of supplements, whose efficacy is potentially affected by inter-individual life style variability, supportive motivation training might be advisable for future clinical trials.