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D. Laddu, C. Dow, M. Hingle, C. Thomson and S. Going, “A Review of Evidence-Based Strategies to Treat Obesity in Adults,” Nutrition in Clinical Practice, Vol. 26, No. 5, 2011, pp. 512-525. doi:10.1177/0884533611418335

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• TITLE: A Pilot Clinical Trial on L-Carnitine Supplementation in Combination with Motivation Training: Effects on Weight Management in Healthy Volunteers

  AUTHORS: Satoshi Odo, Koji Tanabe, Masamitsu Yamauchi

  KEYWORDS: L-Carnitine; Weight Management; Motivation Training; Carnipure?

  JOURNAL NAME: Food and Nutrition Sciences, Vol.4 No.2, February 26, 2013

  ABSTRACT: A 4-week low dosage (500 mg/day) L-carnitine supplementation in combination with motivation training was carried out in 24 overweight (BMI 25.8 - 26.6 kg/m2) Japanese males in the course of a double-blind randomized placebo-controlled study. L-carnitine motivated group showed significant body weight loss and a decrement of serum triglyceride level vs. the non-motivated placebo group. Serum adiponectin levels increased in both L-carnitine supplemented groups. The beneficial effects of L-carnitine were amplified by motivation training. For clinical evaluation of supplements, whose efficacy is potentially affected by inter-individual life style variability, supportive motivation training might be advisable for future clinical trials.