TITLE:
A Pilot Clinical Trial on L-Carnitine Supplementation in Combination with Motivation Training: Effects on Weight Management in Healthy Volunteers
AUTHORS:
Satoshi Odo, Koji Tanabe, Masamitsu Yamauchi
KEYWORDS:
L-Carnitine; Weight Management; Motivation Training; Carnipure?
JOURNAL NAME:
Food and Nutrition Sciences,
Vol.4 No.2,
February
26,
2013
ABSTRACT: A 4-week low dosage (500 mg/day) L-carnitine supplementation in combination with motivation training was carried out in 24 overweight (BMI 25.8 - 26.6 kg/m2) Japanese males in the course of a double-blind randomized placebo-controlled study. L-carnitine motivated group showed significant body weight loss and a decrement of serum triglyceride level vs. the non-motivated placebo group. Serum adiponectin levels increased in both L-carnitine supplemented groups. The beneficial effects of L-carnitine were amplified by motivation training. For clinical evaluation of supplements, whose efficacy is potentially affected by inter-individual life style variability, supportive motivation training might be advisable for future clinical trials.