TITLE:
Myxoid Meningioma: An Example of a Rare Brain Tumour of Difficult Diagnosis
AUTHORS:
Javier Ortiz, María Dolores Ludeña, Jesús Gonçalves, Sofía Del Carmen, Ángel Maillo, Agustín Bullon
KEYWORDS:
Myxoid Meningioma; Immunohistochemistry; Electron Microscopy
JOURNAL NAME:
Open Journal of Pathology,
Vol.3 No.1,
January
29,
2013
ABSTRACT: We present a case of a Myxoid Meningioma noticed in a 43-year-old woman. The patient, who had no noteworthy medical antecedents, showed repeated focal epileptic crisis. Imaging studies (MR and CT) showed a solitary and well delimited tumour located in the frontral lobe. Once extirpated, the histological study revealed a neoplasm of myxoid and benign appearance, with elongated and uniform cells, with no atypias and a very low mitotic index. Immunohistochemisty studies (positivity for Vimentin and Epithelial Membrane Antigen, and negativity for the other markers) as well as physical and radiological examination of the patient (absence of tumours in any other location), suggested the diagnosis of a Myxoid Meningioma, which was confirmed by electron microscopy (by the presence of desmosomes). We also revise the characteristics of Myxoid Meningiomas, an absolutely exceptional primary tumour of the central nervous system.