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S. M. Nimjee, C. J. Powers and K. R. Bulsara, , “Review of the Literature on the Novo Formation of Cavernous Malformations of the Central Nervous System after Radiation Therapy,” Neurosurgical Focus, Vol. 21, No. 1, 2006, p. e4.

has been cited by the following article:

• TITLE: De Novo Cavernous Malformation after Radiosurgery

  AUTHORS: Catarina Viegas, Bruno Santiago, Joana Boléo Tomé, Manuel Cunhae Sá

  KEYWORDS: Cavernous Malformation; Radiosurgery; Radiation Induced Cavernoma; Grade II Astrocytoma

  JOURNAL NAME: Open Journal of Modern Neurosurgery, Vol.3 No.1, January 28, 2013

  ABSTRACT: Background: The general use of radiation therapy and radiosurgery as first-line or adjuvant treatment of central nervous system (CNS) lesions has been associated with several harmful effects. Case Description: We report the case of a 16-year-old male patient, submitted at the age of seven to surgical removal of a world heath organization (WHO) grade II diffuse astrocytoma and referred for adjuvant radiosurgery after three further surgeries due to local recurrences. Seven years after radiosurgical treatment, he presented with symptoms of intracranial hypertension. Magnetic resonance imaging (MRI) at the time showed a cavernous malformation in the tumor bed, histologically confirmed, without tumoral recurrence. Conclusion: This case report emphasizes the relation between radiosurgery and the appearance of the novo cavernous malformations, only described previously in one adult patient.