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J. E. Moyron-Quiroz, J. Rangel-Moreno, K. Kusser, L. Hartson, F. Spraque, S. Goodrich, D. L. Woodland, F. E. Lund and T. D. Randall, “Role of Inducible Bronchus Associated Lymphoid Tissue (iBALT) in Respiratory Immunity,” Nature Medicine, Vol. 10, No. 9, 2004, pp. 927-934. doi:10.1038/nm1091

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• TITLE: Kikuchi-Fujimoto Disease in Patients with Sjögren’s Syndrome

  AUTHORS: Lida Radfar, Mehdi Radfar, Kathy L. Moser, Robert Hal Scofield

  KEYWORDS: Sjögren’s Syndrome; Kikuchi-Fujimoto Disease

  JOURNAL NAME: Open Journal of Pathology, Vol.3 No.1, January 28, 2013

  ABSTRACT: Sjogren’s syndrome is a chronic autoimmune exocrinopathy associated with dry eyes and dry mouth as major clinical manifestations. It is characterized by lymphocytic infiltration of lacrimal and salivary glands and autoantibody production, especially anti-Ro (or SSA) and anti-La (or SSB). Lymphoproliferative disorders are a feature of Sjogren’s syndrome, and can be considered an extraglandular manifestation of the disease. Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is a rare form of lymphadenitis. It is reported more often in young adult women with localized lymphadenopathy (usually cervical), fever, rashes, and leukopenia. It is a self-limiting disease with resolution within 1 - 4 months in almost all patients. Sjogren’s syndrome has been reported in patients with other systemic diseases including SLE and lymphomas. Here we present a patient with Kikuchi-Fujimoto disease who developed Sjogren’s Syndrome 8 years after her diagnosis of Kikuchi-Fujimoto disease.