TITLE:
Competition of Aromatic Bromination and Nitration in Concentrated Sulfuric Acid
AUTHORS:
Alexander M. Andrievsky, Mikhail V. Gorelik
KEYWORDS:
Bromination; Nitration; Aromatic Compounds; 5-Bromo-1, 3-dinitrobenzene; 5-Bromo-2, 4, 7-trinitrofluorenone; 4-Bromo-2, 7-dinitrophenanthrenquinone
JOURNAL NAME:
Open Journal of Synthesis Theory and Applications,
Vol.2 No.1,
January
28,
2013
ABSTRACT: Composition of bromine and nitric acid in concentrated sulfuric acid is effective for bromination of strongly deactivated aromatic compounds and for nitration and bromination of moderately deactivated compounds in one stage. The question why brominating agent is more reactive than nitrating agent in relation to strongly deactivated aromatic compounds and is less reactive in relation to moderate deactivated ones is discussed.