TITLE:
Creatine supplementation in exercised rats: Effects on the aerobic capacity
AUTHORS:
Michel Barbosa de Araújo, Roberto C. Vieira Junior, Leandro P. Moura, Marcelo Costa Junior, Rodrigo A. Dalia, Amanda Christine da Silva Sponton, Carla Ribeiro, Maria Alice R. Mello
KEYWORDS:
Diet; Lactate; Maximal Lactate Steady State; Treadmill Running
JOURNAL NAME:
Open Journal of Animal Sciences,
Vol.3 No.1,
January
24,
2013
ABSTRACT: This study aimed to analyze the possible metabolic
disturbances caused by creatine supplementation on aerobic capacity of rats,
inferred by the maximal lactate steady state. Forty male Wistar rats (90 days old) were distributed
into two groups for eight weeks: trained group (T): rats that were submitted to
a training protocol, and supplemented-trained group (TCr): rats that were submitted to a training protocol and received balanced diet supplemented with 2% creatine. The blood lactate concentrations
equivalent to maximal lactate steady state during treadmill running were
analyzed at the beginning and also at the end of the experiment. At the end of
the experiment were done comparing the test
results MLSS between the two groups. At the beginning of the experiment,
prior to groups division, the majority of animals obtained MLSS at a speed of26 m/min, blood lactate concentration of 3.79
± 0.76 mmol/L. At the end of the experiment, most of trained rats in T
presented MLSS at the speed of28 m/min,
blood lactate concentration of 3.37 ± 0.68 mmol/L. Most TCr had MLSS at the
speed of28 m/min, blood lactate
concentration of 3.52 ± 0.69 mmol/L. We conclude that creatine supplementation
was not the cause of the improvement in the aerobic capacity of rats in the
tread-mill exercise.