TITLE:
Inorganic Molecularly Imprinted Polymer by Sol-Gel Process for Recognition of Caffeine
AUTHORS:
Min Jae Shin, Young Jae Shin, Jae Sup Shin
KEYWORDS:
Molecularly Imprinted Polymer; Sol-Gel Process; Caffeine; Theophylline
JOURNAL NAME:
Open Journal of Organic Polymer Materials,
Vol.3 No.1,
January
24,
2013
ABSTRACT: A molecularly imprinted polymer (MIP) was formed using an inorganic polymer by a sol-gel process. The monomers which were used to synthesize the inorganic polymer were tetraethoxysilane (TEOS), triethoxymethylsilane (MTES), and triethoxyphenylsilane (PTES). Caffeine was chosen as a template for the molecular imprinting, and theophylline was chosen as the analogous counterpart compound. The discriminating ability of the synthesized MIP to these two-compounds was estimated in this study. The MIP showed the highest discriminating ability when the ratio of TEOS:MTES: PTES in the synthesis of the inorganic polymer was 1:1:3, the reaction temperature was 50?C, and the pH of the reaction system was ~6.5.