Article citationsMore>>
E. Jabbour and H. Kantarjian, “Chronic Myeloid Leukaemia: 2012 Update of Diagnosis, Monitoring and Management,” American Journal of Hematology, Vol. 87, No. 11, 2012, pp. 1037-1045. doi;10.1002/ajh.23282
has been cited by the following article:
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TITLE:
Dasatinib-Induced Hepatic Dysfunction
AUTHORS:
Arumugam Manoharan
KEYWORDS:
Dasatinib; Hepatic Dysfunction; Reversibility
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.4 No.1,
January
18,
2013
ABSTRACT: A 53-year-old man with chronic myeloid leukaemia developed significant hepatic dysfunction when treatment was changed from imatinib (because of drug-induced rash) to dasatinib. Liver function tests returned to normal 77 days after cessation of therapy and have remained normal despite recommencement of dasatinib. Although the pathogenesis for the significant hepatic dysfunction is unclear, this case illustrates the reversibility of this event with dose interruption and that dasatinib can be safely recommenced for ongoing treatment.