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Savvateeva L. V., Gorokhovets N. V., Makarov V. A., Posypanova G. A., Severin S. E., Recombinant third domain of human alpha-fetoprotein: selectivity and antitumor activity of conjugate with Taxol. Abstracts of the XXXIII Meeting of the International Society for Oncodevelopmental Biology and Medicine (ISOBM), Rhodes, Greece, p. 84., September 2005.

has been cited by the following article:

• TITLE: Conjugation of the Recombinant Third Domain of Human Alpha-fetoprotein with Doxorubicin Using Poly(amidoamine) Dendrimers and Study of Its Cytotoxic Activity

  AUTHORS: S. I. Kisil, V. A. Chernikov, M. I. Danilevskiy, L. V. Savvateeva, N. V. Gorokhovets

  KEYWORDS: Alpha-fetoprotein; Dendrimer; Doxorubicin; Targeted Delivery

  JOURNAL NAME: Engineering, Vol.4 No.10B, January 17, 2013

  ABSTRACT: The recombinant third domain of alpha-fetoprotein (AFP3D) is one of the promising vectors for targeted delivery of anticancer drugs to tumor cells. AFP3D-based conjugates with various anti-tumor agents have shown specific anti-tumor activity. The content of anti-tumor drugs in the preparation could be increased by including dendrimers - highly branched nanoparticles - into a targeted delivery system. In this study, we synthesized the AFP3D conjugate with doxorubicin-loaded poly(amidoamine) (PAMAM) dendrimer nanoparticles and investigated its cytotoxic activity.