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S. Laycock-van Spyk, N. Thomas, D. N. Cooper and M. Upadhyaya, “Neurofibromatosis Type 1-Associated Tumours: Their Somatic Mutational Spectrum and Pathogenesis,” Hum Genomics, No. 5, Vol. 6, 2011, pp. 623-690.

has been cited by the following article:

• TITLE: Concomitant Occurrence of Segmental Neurofibromatosis and Lung Adenocarcinoma

  AUTHORS: Ryoko Morita, Naoki Oiso, Akira Kawada

  KEYWORDS: Segmental Neurofibromatosis; Lung Adenocarcinoma; Internal Malignant Tumors

  JOURNAL NAME: Journal of Cosmetics, Dermatological Sciences and Applications, Vol.2 No.4, December 27, 2012

  ABSTRACT: Neurofibromatosis type 1 (NF1) caused by a loss-of functional mutation in NF1 encoding neurofibromin is an autosomal dominant disorder characterized by café-au-lait spots, neurofibromas, intertriginous freckles, and Lisch nodules. Segmental neurofibromatosis (SN) represents a postzygotic mutation and loss of heterozygosity in neurofibromin. SN occurring in the elder persons may be associated with internal malignant tumors. Here, we reported a case of 58-year-old woman with concomitant occurrence of SN and lung adenocarcinoma. The onset of SN in aged persons would be a sign of concomitant occurrence of internal malignant tumors.