Article citationsMore>>

J. R. Harding, R. A. Hughes, N. M. Kelly, A. Sutherland and C. L. Willis, “Synthesis of Isotopically Labelled L-aAmino Acid with an Asymmetric Centre at C-3”, Journal of the Chemical Society, Perkin Transactions 1, Vol. 2000, 2000, pp. 3406-3416. doi:10.1039/b005172l

has been cited by the following article:

• TITLE: Ti(IV) Chloride-Promoted Diastereoselective Conjugate Addition of 1-Enoyl-5-substituted Hydantoins with Allyltrimethylsilane

  AUTHORS: Jun-ichi Yamaguchi, Kanako Nozaki Abe, Takayuki Suyama

  KEYWORDS: Hydantoin; Conjugate Addition; Lewis Acid; Allyltrimethylsilane

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.2 No.4, December 27, 2012

  ABSTRACT: Diastereoselective conjugate addition of 1-enoyl-5-substituted hydantoins with allyltrimethylsilane in the presence of Ti(IV) chloride proceeded to give the corresponding allyl adducts in high yield and high diastereoselectivity. In order to determine the absolute configuration on the β-position of the acyl group, the hydantoin was removed by hydrolysis of the allyl adducts with a base to give the corresponding carboxylic acid. It was found that the absolute configuration was S on the basis of specific rotation.