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B. Christian, W. Zhao, M. Hamadani, E. M. Sotomayor, W. Navarro, S. M. Devine, F. Racke and K. A. Blum, “Mantle Cell Lymphoma 12 Years after Allogeneic Bone Marrow Transplantation Occurring Simultaneously in Recipient and Donor,” Journal of Clinical Oncology, Vol. 28, No. 31, 2010, pp. e629-e632. doi:10.1200/JCO.2010.29.8992

has been cited by the following article:

• TITLE: Collision Anaplastic Large Cell Lymphoma (T-Cell/Histiocyte-Rich) and Diffuse Large B Cell Lymphoma: A Pathologic and Clinical Evaluation

  AUTHORS: Lakshmi Rajappannair, Elaine Lam, Don Benson, Frederick Racke, Steven Devine, Weiqiang Zhao

  KEYWORDS: Collision Lymphoma; ALCL; DLBCL

  JOURNAL NAME: Journal of Cancer Therapy, Vol.3 No.6, December 14, 2012

  ABSTRACT: A collision tumor of T and B-cell lymphomas occur rarely. In this article we report a collision tumor of anaplastic large cell lymphoma and diffuse large B cell lymphoma in a 46 year old female. The tumor showed predominantly neoplastic anaplastic large cell lymphoma (ALCL) component expressing CD30 and ALK with smaller areas of CD20+ diffuse large B cell lymphoma component. Polymerase chain reaction for T-cell receptor beta and IgH (VDJ) gene rearrangements detected a clonal T cell and a clonal B cell population. The patient developed CSF involvement approximately 3 months after treatment. CSF analysis at this time showed only monoclonal T cells, probably due to clearing of the B cell component by the chemotherapy. To the best of our knowledge this is the first case report of a composite tumor of ALCL (lymphohistiocytic variant) and DLBCL. This case raises issues related to the classification of these composite lymphomas and the treatment on initial presentation and during relapse.