TITLE:
Thymic langerhans cell histiocytosis in children: A case report
AUTHORS:
Marie Poncelet, Camille Chabert, Jean Pierre Pracros, Perrine Marec Berard
KEYWORDS:
Langerhans Cell Histiocytosis; Children; Thymus
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.2 No.4,
December
13,
2012
ABSTRACT: Langerhans cell histiocytosis has long been described as a rare systemic disorder involving the proliferation of Langerhans cells with formation of granuloma. The disease may be localised or diffuse. Typical forms of the disease involving the bone, the skin or the pituitary gland have been well described whereas others, such as thymic histiocytosis, are still poorly understood. Here, we report a case of isolated Langerhans cell histiocytosis of the thymus in an infant with non-specific symptoms. We provide a description of the disease and discuss patient management.