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Johnson, A.M., Alper, C.A., Rosen, F.S. and Craig, J.M. (1971) C1 inhibitor: Evidence for decreased hepatic synthesis in hereditary angioneurotic edema. Science, 173, 553-554. doi:10.1126/science.173.3996.553

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• TITLE: Perioperative anesthetic management in pediatric hereditary angioedema; case report

  AUTHORS: M. Nuri Deniz, Aylin Incesu, Elvan Erhan, Gulden Ugur

  KEYWORDS: Hereditary Angioedema; C1 Inhibitor Deficiency; Anesthetic Management and Bladder Tumor

  JOURNAL NAME: Open Journal of Pediatrics, Vol.2 No.4, December 13, 2012

  ABSTRACT: Hereditary angioedema is a rare but life-threatening disease, usually resulting from upper respiratory tract traumas and stress. In this case report, we present the management of a 14-year-old female patient who was diagnosed with hereditary angioedema and scheduled to undergo transurethral resection of bladder (TURB) procedure for bladder tumor. She was on prophylactic danazol treatment and prior to the operation the dose of danazol was increased. On the day of the operation, patient was given C1-IHN concentrate and was sedated. In conclusion, hereditary angioedema is a rare disease in which multidisciplinary and aggressive approach during anesthesia would yield successful results.