Article citationsMore>>

Diarra, M.S., Silversides, F.G., Diarrasouba, F., Pritchard, J., Masson, L., Brouseau, R., Bonnet, C., Delaquis, P., Bach, S., Skura, B.J. and Topp, E. (2007) Impact of food supplementation with antimicrobial agents on growth performance of broiler chickens, Clostridium perfringes and enterococcus counts and antibiotic resistance phenotypes and distribution of antimicrobial resistance determinants in Escherichia coli isolates. Environmental Microbiology, 73, 6566-6576. doi:10.1128/AEM.01086-07

has been cited by the following article:

• TITLE: Effective treatment of resistant Escherichia coli infection, with sulphadimidine stabilized in a synthetic Aluminium-Magnesium Silicate

  AUTHORS: Maduike C. O. Ezeibe, Uchenna M. Chima, Augustine A. Ngene, Obianuju N. Okoroafor, Idika I. Kalu, Mfon E. Esen

  KEYWORDS: Resistant Pathogens; Escherichia coli; Sulphadimidine; Aluminium-Magnesium Silicate;Nanoparticles

  JOURNAL NAME: Health, Vol.4 No.12, December 12, 2012

  ABSTRACT: To investigate if Aluminium-Magnesium Silicate (AMS) could make drugs regain effects against resistant pathogens, its effect was tested on sulphadimidine against sulphadimidine-resistant Escherichia coli. Two groups of chicks infected with sulphadimidine-resistant E. coli were treated at sulphadimidine dose rate of 1 g/litre of drinking water, with sulphadimidine and with an AMS-sulphadimidine drug formulation, respectively. Two other groups were similarly treated at sulphadimidine dose rate of 0.75 g/litre, while the fifth group served as control. Mean titres of the bacterium in bile of the chicks were compared. Titres, 119,200 ± 55,800 CFU/mL of the group treated with sulphadimidine at rate of 1 g/ litre and 14,800 ± 1700 CFU/mL of the group treated at rate of 0.75 g/litre, did not vary from 33,200 ± 5200 CFU/mL of the control (P > 0.05) but 295,200 ± 106,400 CFU/ml of the group treated at rate of 1 g/litre, with the AMS-sulpha- dimidine drug was significantly (P