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S. Lutz, S. S. Lo, E. Chow, A. Sahgal and P. Hoskin, “Radiotherapy for Metastatic Bone Disease: Current Standards and Future Prospectus,” Expert Review of Anticancer Therapy, Vol. 10, No. 5, 2010, pp. 683-695. doi:10.1586/era.10.32

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• TITLE: Assessing Patient Outcomes after Palliative Radiotherapy Using IG-IMRT

  AUTHORS: Rajiv Samant, Michael Scopazzi, Kathy Carty

  KEYWORDS: Radiotherapy; Palliation; Symptom Improvement; IG-IMRT

  JOURNAL NAME: Journal of Cancer Therapy, Vol.3 No.6, December 6, 2012

  ABSTRACT: Purpose: To assess clinical outcomes after using IG-IMRT for palliation among patients with advanced cancers. Methods: Patients with advanced and/or metastatic cancers were treated on our Tomo-PAL (Tomotherapy?-Planning and Administration Linked) protocol using helical TomoTherapy? and evaluated to assess clinical efficacy of treatment as well as to assess side effects. Results: A total of 40 patients were treated to 40 sites from Feb 2007 to May 2009. There were 25 men and 15 women with a median age of 70 years (range 16 - 94). Pain and bleeding were the most common symptoms being palliated (80% and 12.5% respectively). The dose prescribed ranged from 5 - 25 Gy in 1 - 5 fractions. A qualitative improvement in symptoms was documented in 82% of patients (75% partial relief and 7% complete relief) and major side effects were not encountered. Conclusions: IG-IMRT can be used for palliation and produces response rates that compare favourably with those reported in the published literature.