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Whittom, F., Jobin, J., Simard, P.M., Leblanc, P., Simard, C. and Bernard, S. (1998) Histochemical and morphological characteristics of the vastus lateralis muscle in patients with chronic obstructive pulmonary disease. Medicine and Science in Sports and Exercise, 30, 1467-1474. doi:10.1097/00005768-199810000-00001

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• TITLE: Effect of pulmonary rehabilitation on oxidative stress in patients with pulmonary diseases

  AUTHORS: Masayuki Itoh, Kenji Nemoto, Takao Tsuji, Hiroyuki Nakamura, Kazutetsu Aoshiba

  KEYWORDS: Pulmonary Rehabilitation; Exercise; Oxidative Stress; Antioxidants; Chronic Obstructive Pulmonary Disease

  JOURNAL NAME: Advances in Bioscience and Biotechnology, Vol.3 No.7A, November 30, 2012

  ABSTRACT: Exercise-training-based pulmonary rehabilitation has been confirmed to be effective in improving the activities of daily living (ADL) and relieving the dyspnea of chronic obstructive pulmonary disease (COPD) patients. Exercise training increases the antioxidant capacity of COPD patients, but since strenuous exercise and acute exercise loading have the opposite effect and increase oxidative stress, it is important to establish exercise training conditions that efficiently raise antioxidant capacity without increasing oxidative stress. Research on oxidative stress during exercise training by COPD patients has been pursued from that standpoint, but in recent years the targets of research on respirator diseases other than COPD have been expanding. In this article we will therefore review the results of research that has been conducted thus far on the effect of pulmonary rehabilitation on oxidative stress, including the results obtained at our own institution.