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Krupp, L.B., Coyle, P.K. and Doscher, C. (1995) Fatigue therapy in multiple svlerosis—Results of a double-blind, randomized, parallel trial of amantadine, remoline, and placebo. Neurology, 45, 1956-1961. doi:10.1212/WNL.45.11.1956

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• TITLE: Non-motor signs and symptoms in Parkinson’s disease

  AUTHORS: Kazuo Abe

  KEYWORDS: Parkinson’s Disease (PD); Non-Motor Signs and Symptoms; Activities of Daily Livings (ADL); Quality of Life (QOL)

  JOURNAL NAME: Health, Vol.4 No.11A, November 29, 2012

  ABSTRACT: Motor symptoms are cardinal clinical features of Parkinson’s disease (PD). Progress in drug therapy and rehabilitation has been presenting beneficial effect for motor symptoms. However, non-motor symptoms and signs in PD have been accumulated growing attentions and its amelioration may also give beneficial effect for PD patients’ and their care givers’ quality of life. In this mini-review, I overviewed non-motor symptoms and signs in PD.