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Gschwandtner, U., Aston, J., Borgwardt, S., Drewe, M., Feinendegen, C., Lacher, D., Lanzarone, A., Stiegliz, R.D. and Riecher-Rossler, A. (2003) Neuropsychological and neurophysiological findings in individuals suspected to be at risk for schizophrenia: preliminary results from the Basel early detection of psychosis study—Fruherkennung von Psychosen (FEPSY). Acta Psychiatrica Scandinavica, 108, 152-155. doi:10.1034/j.1600-0447.2003.00157.x

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• TITLE: Behavioral inhibition in female college students with schizotypal traits: An event-related potential study

  AUTHORS: Ji-Hyun Lee, Myung-Sun Kim

  KEYWORDS: Behavioral Inhibition; Event-Related Potentials; Go/NoGo Task; N2; P3; Schizotypal Trait

  JOURNAL NAME: Open Journal of Psychiatry, Vol.2 No.4, November 27, 2012

  ABSTRACT: This study investigated behavioral inhibition in female college students with psychometrically defined schizotypal traits using a Go/NoGo task and event-related potentials (ERPs). The schizotypal-trait (n = 15) and normal control (n = 15) groups were selected based on scores of the Schizotypal Personality Questionnaire (SPQ). The Go/NoGo task consisted of Go (requires response) and NoGo (requires no response) conditions. In terms of response time and accuracy rate for the Go/NoGo task, the two groups did not differ significantly. In terms of ERPs, the control group showed greater N2 amplitudes in response to NoGo (NoGo-N2) than to Go stimuli (Go-N2), whereas the schizotypal-trait group showed no significant difference in NoGo-N2 and Go-N2 amplitudes. In addition, the schizotypal-trait group showed reduced NoGo-N2 amplitudes at the frontal site compared to controls, and an association between SPQ scores and NoGo-N2 amplitudes measured at the frontal site. The two groups did not differ in P3 amplitudes. Since the N2 reflects the detection of response conflict and behavioral inhibition, the present results indicate that nonclinical individuals with schizotypal traits have difficulties in detecting response conflict and behavioral inhibition.