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Verdecchia, P., Reboldi, G., Schillaci, G., Borgioni, C., Ciucci, A., Telera, M.P., et al. (1999) Circulating Insulin and Insulin Growth Factor-1 Are Independent Determinants of Left Ventricular Mass and Geometry in Essential Hypertension. Circulation, 100, 1802-1807.

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• TITLE: Atrial fibrillation in diabetes: A cause for concern?

  AUTHORS: Benjamin R. Szwejkowski, Sushma Rekhraj, Andrew D. Morris, Allan D. Struthers

  KEYWORDS: Diabetes; Atrial Fibrillation; Mechanisms; Treatment

  JOURNAL NAME: Journal of Diabetes Mellitus, Vol.2 No.4, November 22, 2012

  ABSTRACT: Atrial fibrillation (AF) is one of the most common cardiac arrhythmias and is associated with significant morbidity and mortality. It is becoming increasingly evident diabetes is a significant risk factor for the development of AF. The reason for this link is not clearly understood, however it is clear that other co-morbid diseases associated with diabetes such as hypertension and obesity may be implicated or there may be direct arrthymogenic affects of glucose dysregulation on the myocardium. The development of AF in patients with diabetes may be an ominous sign given the increased risk of death from cardiovascular disease and we propose this is an under researched area where treatments may bring benefits over and above those patients without diabetes in terms of morbidity or death from cardiovascular disease.