TITLE:
Evaluation of Visceral and Subcutaneous Fat by Ultrasound and Its Relationship with Clinical and Metabolic Parameters of Insulin Resistance and Subclinical Atherosclerosis
AUTHORS:
Clarisse Miranda Prado, Germana Augusto de Vasconcelos, Emmanuelle Tenorio A. M. Godoi, Érica Nogueira Bezerra Cavalcanti, Tiago Matos de Arruda, Erik Trovão Diniz, Cynthia Salgado Lucena, Luiz Griz, Francisco Bandeira
KEYWORDS:
Visceral Fat Thickness; Subcutaneous Fat Thickness; Preperitoneal Circumference; Carotid Intima-Media Thickness; Metabolic Syndrome
JOURNAL NAME:
Open Journal of Endocrine and Metabolic Diseases,
Vol.2 No.4,
November
19,
2012
ABSTRACT: Objective: this study set out to investigate the association between abdominal obesity ultrasound measurements, waist circumference and body mass index (BMI), metabolic syndrome (MS) components and subclinical atherosclerosis. Methods: sixty patients were recruited and divided equally into two groups, according to the presence of MS. All subjects had an ultrasound examination for measurement of visceral and subcutaneous fat thickness and carotid IMT. Results: the values of visceral fat thickness, preperitoneal circumference and carotid IMT were higher in patients with MS than in control subjects. Visceral fat thickness showed significant correlations with many cardiovascular risk factors (waist circumference, BMI, fasting plasma glucose, HDL and LDL cholesterol). All abdominal obesity measurements were correlated with BMI. Carotid IMT showed correlations with age, visceral fat and preperitoneal circumference. Visceral fat was independently associated with systolic and diastolic blood pressures and fasting plasma glucose. Systolic and diastolic blood pressures and BMI were independent determinants of carotid IMT. Conclusion: visceral fat thickness showed the best correlation with MS components, suggesting that it could be a useful parameter in cardiovascular risk assessment. Age, systolic and diastolic blood pressures and BMI were independent determinants of subclinical atherosclerosis. MS was associated with a higher carotid IMT.