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M. J. Sack, C. Astengo-Osuna, B. T. Lin, H. Battifora and V. A. LiVolsi, “HBME-1 Immunostaining in Thyroid Fine-Needle Aspirations: A Useful Marker in the Diagnosis of Carcinoma,” Modern Pathology, Vol. 10, No. 7, 1997, pp. 668-674.

has been cited by the following article:

• TITLE: The Utility of Fine-Needle Aspiration in the Diagnosis and Management of Follicular Thyroid Neoplasms:One Institution’s 10-Year Experience

  AUTHORS: Robert Deeb, Osama Alassi, Saurabh Sharma, Mei Lu, Tamer Ghanem

  KEYWORDS: Fine Needle Aspiration; Follicular; Thyroid; Adenoma; Carcinoma

  JOURNAL NAME: International Journal of Otolaryngology and Head & Neck Surgery, Vol.1 No.2, August 20, 2012

  ABSTRACT: Background: Classical teaching dictates that follicular adenoma (FA) can be distinguished from follicular carcinoma (FC) based on histologic features only. We retrospectively reviewed our institution’s 10-year experience in the use of fine-needle aspiration (FNA) to diagnose follicular thyroid neoplasms. Methods: Patients who had FNA of a thyroid neoplasm from 2000 to 2010 were reviewed. Diagnoses of FA, FC, or follicular neoplasm-not otherwise specified (NOS) were included. Cytopathological results were correlated with surgical pathology. Results: Of 138 patients, 65% underwent surgery. FNA diagnosis for FA had a sensitivity of 50% and specificity of 71%. 25% of patients with an FNA diagnosis of FA were found to have cancer after surgical specimen examination. FNA diagnosis for FC had a sensitivity of 60% and specificity of 94%. Conclusions: FNA has a low sensitivity for diagnosing FA. Surgical pathology remains the gold standard for differentiating follicular carcinoma from adenoma.