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Peto, R., Pike, M.C., Day, N.E., Gray, R.G.K, Lee, P.N. Parish, S., Peto, J., Richards, S. and Wahrendorf, J. (1980) Guidelines for sample sensitive significance test for carcinogenic effects in long-term animal experiments. IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Suppl. 2, Long-Term and Short-Term Screening Assays for Carcinogens: A Critical Appraisal, IARC, Lyon, 311-426.

has been cited by the following article:

• TITLE: Pairwise comparisons in the analysis of carcinogenicity data

  AUTHORS: Mohammad A. Rahman, Ram C. Tiwari

  KEYWORDS: Carcinogenicity Study; Trend Test; Pairwise Test; Exact Test

  JOURNAL NAME: Health, Vol.4 No.10, November 1, 2012

  ABSTRACT: Analysis of carcinogenicity data generally involves a trend test across all dose groups and a pairwise comparison of the high dose group with the control. The most commonly used test for a positive trend is the Cochran-Armitage test. This test is asymptotically normal. For the pairwise comparison of the high dose group with the control group, we propose two modifications: the first modification is to apply the test on the data from high dose and control groups after dropping the data from the low and the medium dose groups; the second modification is to adjust the test conditional on data from all dose groups. We compare the power performance of these two modifications for the pairwise comparisons.