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Abraham, W.T., Fisher, W.G., Smith, A.L., Hayes, D.L., Ellestad, M., Trupp, R.J., Underwood, J., et al. (2002) MIRA CLE study group. Multicenter insync randomized clinical evaluation: Cardiac resynchronization in chronic heart failure. The New England Journal of Medicine, 346, 1845-1853. doi:10.1056/NEJMoa013168

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• TITLE: Improvement in MR and in the dyssynchrony between the mid segments predict super responders in patients undergoing CRT

  AUTHORS: Miry Blich, Shemy Carasso, Mahmoud Suleiman, Ibrahim Marai, Tawfig Zeidan Shwiri, Lior Gepstein, Monther Boulos

  KEYWORDS: Mitral Regurgitation; Cardiac Resynchronization Therapy

  JOURNAL NAME: World Journal of Cardiovascular Diseases, Vol.2 No.4, October 30, 2012

  ABSTRACT: Background: Twenty to thirty percent of patients with left heart failure in randomized trials do not respond clinically to cardiac resynchronization therapy (CRT). The objectives of our work were to estimate the effec-tiveness of CRT in our routine practice, and to find predictors of favorable response to CRT. Methods: Retrospective analysis of consecutive patients who underwent CRT from 2003-2007. Results: Fifty six consecutive patients (73.2% men, age 66.3 ± 10.2 years) with left heart failure (LHF) (ischemic cardiomyopathy 60.7%) received CRT and were followed for a mean of 27 months. After the implantation: Mean NYHA improved by one class (p