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R. Gonzalez, N. Martin, C. Seoane, J. L. Marco, A. Albert and F. H. Cano, “The First Asymmetric Synthesis of Poly- functionalized 4H-pyrans via Michael Addition to Malo- nonitrile to 2-Acyl Acrylates,” Tet-rahedron Letters, Vol. 33, No. 26, 1992, pp. 3809-3812.

has been cited by the following article:

• TITLE: KF-Al2O3 as an Efficient and Recyclable Basic Catalyst for the Synthesis of 4H-Pyran-3-carboxylates and 5-Acetyl-4H-pyrans

  AUTHORS: Iadeishisha Kharbangar, Md. Rumum Rohman, Hormi Mecadon, Bekington Myrboh

  KEYWORDS: 4H-Pyran derivatives; Ethanol; KF-Al2O3; Room Temperature; Three-Component

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.2 No.3, September 28, 2012

  ABSTRACT: KF-Al2O3 as a recyclable basic catalyst for the three-component synthesis of 4H-pyran derivatives by the reaction of aldehydes, malononitrile and active methylene dicarbonyl compounds in ethanol at room temperature is described. The protocol is environmentally benign and offers rapid access to a wide array of 4H-pyran heterocycles in good to excellent yields.