TITLE:
Isolated gonadotropin deficiency with primary empty sella: Causal or casual association?
AUTHORS:
Shashank Shekhar, Chanderdeep Sharma, Mukesh Surya, Neeti Aggarwal
KEYWORDS:
Empty Sella; Empty Sella Syndrome; Gonadotropin Deficiency
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.2 No.3,
September
7,
2012
ABSTRACT: Empty sella is a radiological-anatomical entity characterised by a sella turcica filled partially or completely with cerebrospinal fluid, leading to varying degrees of pituitary flattening. Literature reports a 5% - 20% incidence of empty sella in unselected autopsies leading many to argue that its an extreme normal variant. Endocrine dysfunction varies from 8% - 25% with primary empty sella with growth hormone deficiency being most common. However isolated gonadotropin deficiency with normal sized primary empty sella are rare if any. We are reporting a case of isolated gonadotropin deficiency with primary empty sella unable to confirm or refute the association as causal or casual.