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Milot, E., Mayer, F. M., Nussey, D. H., Boisvert, M., Pelletier, F., & Réale, D. (2011). Evidence for evolution in response to natural selection in a contemporary human population, Proceedings of the National Academy of Sciences of USA, 108, 17040-17045. doi:10.1073/pnas.1104210108

has been cited by the following article:

• TITLE: Tay-Sachs and French Canadians: A Case of Gene-Culture Co-evolution?

  AUTHORS: Peter Frost

  KEYWORDS: Neurological Disorder

  JOURNAL NAME: Advances in Anthropology, Vol.2 No.3, August 20, 2012

  ABSTRACT: Tay-Sachs, an inherited neurological disorder, is unusually common among French Canadians from eastern Quebec. Two alleles are responsible, one being specific to the north shore of the St. Lawrence and the other to the south shore. This pattern of convergent evolution suggests the presence of a selection pressure limited to eastern Quebec. Both alleles probably arose after the British conquest of Quebec in 1759 or at least were uncommon previously. To explain the high incidence of Tay-Sachs among Ashkenazi Jews, some authors have invoked heterozygote advantage, i.e., heterozygous individuals enjoy a higher rate of neuronal growth, and thus greater learning capacity, without the neurological deterioration of homozygous individuals. Such an advantage would have helped Ashkenazim perform the mental effort required for work in trade and crafts. A similar situation may have developed in eastern Quebec, where the relative scarcity of British and American merchants made it easier for French Canadians to enter occupations that required literacy, numeracy, and future time orientation.