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J. Felieu, M. Gonzalez Baron, E. Espinosa, C. Garcia Giron, I. de la Gandara, J. Espinosa, A. Colmenarejo, J. I. Jalon, Y. Femandez and J. de Castro, “Uracil and Tegafur Modulated with Leucovorin; an Effective Regimen with Low Toxicity for the Treatment of Colorectal Carcinoma in the Elderly,” Cancer, Vol. 79, No. 10, 1997, pp. 1884 1889.

has been cited by the following article:

• TITLE: A Case of Advanced Multiple Hepatocellular Carcinomas with Portal Vein Tumor Thrombosis Successfully Treated by Oral Tegafur/Uracil

  AUTHORS: Hiroto Tanaka, Huuta Koga, Masako Hasegawa, Hiroshi Takihara, Eri Kimura, Tarou Inoue, Chie Ueda, Wataru Ono, Seigou Takamatsu, Yasushi Nakamura, Hiroki Ueda

  KEYWORDS: Advanced Hepatocellular Carcinoma, Portal Vein Thrombosis, Oral Tegafur/Uracil, Chemotherapy

  JOURNAL NAME: Journal of Cancer Therapy, Vol.1 No.3, September 26, 2010

  ABSTRACT: A case of advanced multiple hepatocellular carcinomas (HCC) with portal vein tumor thrombosis successfully treated by oral tegafur/uracil is reported. A 69-year-old Japanese woman with advanced HCC with tumor thrombosis underwent transcatheter arterial infusion chemotherapy in April 2001. However, 1 year later, the patient experieced a recurrence with advanced multiple HCC with portal vein tumor thrombosis and ascites. Treatment with oral tegafur/uracil was started in May 2002 and resulted in the partial response of liver tumors and the complete improvement of ascites. She remained in good health for about 6 years. This case strongly suggests that oral tegafur/uracil is an effective treatment for some cases of advanced HCC with portal vein tumor thrombosis.