TITLE:
A Case of Advanced Multiple Hepatocellular Carcinomas with Portal Vein Tumor Thrombosis Successfully Treated by Oral Tegafur/Uracil
AUTHORS:
Hiroto Tanaka, Huuta Koga, Masako Hasegawa, Hiroshi Takihara, Eri Kimura, Tarou Inoue, Chie Ueda, Wataru Ono, Seigou Takamatsu, Yasushi Nakamura, Hiroki Ueda
KEYWORDS:
Advanced Hepatocellular Carcinoma, Portal Vein Thrombosis, Oral Tegafur/Uracil, Chemotherapy
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.1 No.3,
September
26,
2010
ABSTRACT: A case of advanced multiple hepatocellular carcinomas (HCC) with portal vein tumor thrombosis successfully treated by oral tegafur/uracil is reported. A 69-year-old Japanese woman with advanced HCC with tumor thrombosis underwent transcatheter arterial infusion chemotherapy in April 2001. However, 1 year later, the patient experieced a recurrence with advanced multiple HCC with portal vein tumor thrombosis and ascites. Treatment with oral tegafur/uracil was started in May 2002 and resulted in the partial response of liver tumors and the complete improvement of ascites. She remained in good health for about 6 years. This case strongly suggests that oral tegafur/uracil is an effective treatment for some cases of advanced HCC with portal vein tumor thrombosis.