TITLE:
Fine needle aspiration cytology in the diagnosis of multiple myeloma
AUTHORS:
Luiz Antonio Guimarães Cabral, Andrea Silveira Penteado, Adriana Aigotti Haberbeck Brandão, Janete Dias Almeida
KEYWORDS:
Multiple Myeloma; Diagnostic Imaging; Cytology
JOURNAL NAME:
Health,
Vol.4 No.8,
August
29,
2012
ABSTRACT: Multiple Myeloma (MM) is a disseminated plasma cell tumor caused by the proliferation of a single plasma cell clone which results from the production of monoclonal immunoglobulin, most commonly class G (IgG). MM is a cancer of the elderly, with a mean age at diagnosis of 68 years. A 79-year-old white patient sought the outpatient clinic of the Discipline of Stomatology, S?o José dos Campos Dental School, UNESP, because of a fracture associated with an osteolytic lesion in the right ascending ramus of the mandible. In view of the clinical-radiographic findings, exploratory fine needle aspiration (FNA) of the lesion was performed and the sanguinolent material obtained was submitted to the preparations of smears for cytology analysis. The diagnosis of MM was based on laboratory and radiographic findings. FNA cytology analysis of the lesion permitted a diagnostic hypothesis of MM.