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L. Wang, P. Park, H. Zhang, F. La Marca and C. Y. Lin, “Prospective Identification of Tumorigenic Osteosarcoma Cancer Stem Cells in OS99-1 Cells Based on High Aldehyde Dehydrogenase Activity,” International Journal of Cancer, Vol. 128, No. 2, 2011, pp. 294-303. doi:10.1002/ijc.25331

has been cited by the following article:

• TITLE: Advancements in Suppression of Osteosarcoma Tumorigenicity: A Prospective Look

  AUTHORS: Lin Wang, Paul Park, Frank La Marca, Khoi Than, Shayan Rahman, Chia-Ying Lin

  KEYWORDS: BMP-2; Osteosarcoma; Cancer Stem Cells; Aldehyde Dehydrogenase

  JOURNAL NAME: Journal of Cancer Therapy, Vol.3 No.4, August 9, 2012

  ABSTRACT: Bone morphogenetic proteins (BMPs) promote differentiation of stem cells into bone cells. Results from our pilot studies indicate these proteins are also capable of inducing the differentiation of stem-like cells that initiate and propagate osteosarcoma, a rare, highly malignant primary bone tumor affecting primarily children and adolescents. Our plans to evaluate the use of BMP as adjuvant therapy to suppress bone tumor while facilitating skeletal reconstruction are reviewed.