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Shanahan, F., Denburg, J.A., Fox, J., Bienenstock, J. and Befus, D. (1985) Mast cell heterogeneity: Effects of neuroenteric peptides on histamine release. The Journal of Immunology, 135, 1331-1337.

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• TITLE: Mast cells and multiple sclerosis in females and males

  AUTHORS: Per Gøran Krüger, Sverre Mørk

  KEYWORDS: Mast Cells; Multiple Sclerosis; Quantification; Females; Males; Treatment

  JOURNAL NAME: World Journal of Neuroscience, Vol.2 No.3, August 23, 2012

  ABSTRACT: Mast cells were observed in autopsies from 11 females and 8 males. We confirm earlier observations that mast cells are more frequent in close vicinity to MS-plaques. In these plaque-border zone areas, defined as the area within 1 mm distance of the actual plaques, the average number of mast cells was 2.34/mm2 in males and 4.77/mm2 in females, which in average is appr. 10 times more than earlier observed in MS. The difference in number of mast cells between females and males is significant (p