TITLE:
Mast cells and multiple sclerosis in females and males
AUTHORS:
Per Gøran Krüger, Sverre Mørk
KEYWORDS:
Mast Cells; Multiple Sclerosis; Quantification; Females; Males; Treatment
JOURNAL NAME:
World Journal of Neuroscience,
Vol.2 No.3,
August
23,
2012
ABSTRACT: Mast cells were observed in autopsies from 11 females and 8 males. We confirm earlier observations that mast cells are more frequent in close vicinity to MS-plaques. In these plaque-border zone areas, defined as the area within 1 mm distance of the actual plaques, the average number of mast cells was 2.34/mm2 in males and 4.77/mm2 in females, which in average is appr. 10 times more than earlier observed in MS. The difference in number of mast cells between females and males is significant (p