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Morejón-Alonso, L., Ferrari, M.B., Camassola, M., Garcia, R. and Santos, L.A. (2010) In vitro citotoxicity of a calcium phosphate-silicate composite bone cement. Proceedings of the 6o Congresso Latinoamericano de órgaos Artificiais e Biomateriais, 17-20 August 2010, Gramado, (RS), Brazil.

has been cited by the following article:

• TITLE: Development and characterization of α-tricalcium phosphate/monocalcium aluminate composite bone cement

  AUTHORS: Loreley Morejón-Alonso, Raúl García Carrodeguas, Luis Alberto dos Santos

  KEYWORDS: Calcium Phosphate Cements; Calcium Aluminate Cements; Hydroxyapatite; In Vitro

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.5 No.8, July 31, 2012

  ABSTRACT: Calcium phosphate cements have received much attention in recent decades owing to their biocompatibility, in situ handling, and shaping abilities. However, their low initial mechanical strength is still a major limitation. On the other hand, calcium aluminate cements (CACs) set fast and have a high initial strength and good corrosion resistance in contact with body fluids, making them excellent dental restorative materials. Therefore, the chemical, mechanical and biological properties of new-TCP/CA cement after aging in simulated body fluid (SBF) were investigated. The results indicated that the composites have setting times not appropriated for immediate applications and have degradation rates higher than those of the traditional CPCs. Moreover, the compressive strength of composite was lower than 5MPa and did not increase with SBF immersion. However, the α-TCP/CA composites showed a higher bioactivity at early stages and were not only more biocompatible but also more noncytotoxic.