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W. Wang, X. X. Cha, J. Reiner, Y. Gao, H. L. Qiao, J. X. Shen, J. B. Chang, “Synthesis and biological activity of n-butylphthalide derivatives,” Eur. J. Med. Chem. Vol. 45, No. 5, 2010, pp. 1941-1946.

has been cited by the following article:

• TITLE: TsOH·H2O-Catalyzed Friedel-Crafts of Indoles of 3-Hydroxyisobenzofuran-1(3H)-One with Indoles: Highly Synthesis of 3-Indolyl-Substituted Phthalides

  AUTHORS: Hongying Tang, Xinyu Zhang, Airu Song, Zhongbiao Zhang

  KEYWORDS: Synthesis; 3-Indolyl-Substituted Phthalides; Friedel-Crafts Alkylation; 3-Hydroxyisobenzofuran-1(3H)-One; Indole

  JOURNAL NAME: Modern Research in Catalysis, Vol.1 No.2, July 24, 2012

  ABSTRACT: An efficient and facile method for the synthesis of 3-indolyl-substituted phthalides by Friedel-Crafts alkylation of indoles with 3-hydroxyisobenzofuran-1(3H)-one has been developed. Using only 2 mol-% TsOH·H2O as the catalyst, various substituted indoles can react smoothly at room temperature to give the corresponding phthalides products in good to excellent yields (up to 96%).