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• TITLE: Risk assessment of alcohol and obesity on liver enzymes (transaminases, cholestatic)

  AUTHORS: Sobia Khawaja, Khalid Mahmood, Alia Munshi, Masarrat Yousuf, Fozia Tabassum, Sohail Shaukat

  KEYWORDS: Moderate Alcohol; Body Mass Index; Obesity; Liver Enzymes

  JOURNAL NAME: Health, Vol.4 No.7, July 20, 2012

  ABSTRACT: Background: This study was designed to investigate the BMI and alcohol consumption effects on hepatic enzymes. The degree of alteration among moderate drinkers is still unclear. Objective: To determine causes of liver failure due to alcohol and obesity. We observed the association between moderate alcohol consumption, body mass index (BMI; in kg/m2) and transaminase, cholestatic enzymes. Design: Serum alanine aminotransferase (ALT), alkaline phosphate (ALP), aspartate aminotransferase (AST), and gammaglutamyltransferase (GGT) were examined in 995 healthy persons. In this study 400 persons were reported as abstainers and 595 participants involved as a moderate drinkers. The study population was further split into according to BMI as follows: