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V. Papaioannou, M. Giannakou, N. Maglaveras, E. Sofianos and M. Giala, “Investigation of Heart Rate and Blood Pressure Variability, Baroreflex Sensitivity, and Approximate Entropy in Acute Brain Injury Patients,” Journal of Critical Care, Vol. 23, No. 3, 2008, pp. 380-386. doi:10.1016/j.jcrc.2007.04.006

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• TITLE: Differences of Heart Rate Variability during Sevoflurane Anesthesia in Children by Age

  AUTHORS: Yong-Hee Park, Chang-Hoon Koo, Jin-Tae Kim, Hee-Soo Kim, Hyo-Jin Byon

  KEYWORDS: Children; Heart Rate Variability; Sevoflurane

  JOURNAL NAME: Open Journal of Anesthesiology, Vol.2 No.3, July 3, 2012

  ABSTRACT: Background: The child’s central nervous system develops with aging, and heart rate variability (HRV), which is con-trolled by the brain, differs from that of adults. We investigated changes in HRV during sevoflurane anesthesia in children. Methods: One 138 children aged from 2 - 12 years without major underlying problems were enrolled. During maintenance with 2 - 2.5 vol% sevoflurane anesthesia, electrocardiographic data were obtained and power spectral analysis, approximate entropy (ApEn) or Hurst exponent were analyzed and compared in three groups (age 2 - 5 years, 6 - 9 and 10 - 12 years of age). Results: The RR interval increased with aging, but low-frequency powers did not. High- frequency power was greater in the oldest children (P