TITLE:
In-vitro Studies of Biologically Important Barium Strontium Chromium Magnesium Hydrogen Phosphate (BaSrCrMgHPO4) Mixed Crystal Growth in SMS Gel Medium at Ambient Temperature and Its Characterization Studies
AUTHORS:
J. Kishore Kumar, P. Ramesh, P. Suresh, P. Sundaramoorthi
KEYWORDS:
In-vitro, Kidney stone
JOURNAL NAME:
Journal of Minerals and Materials Characterization and Engineering,
Vol.9 No.2,
February
20,
2010
ABSTRACT: Kidney stone consists of various compounds. Mineral oxalate monohydrate and di-hydrate are
the main constituent of kidney stones. However, the formation of calcium oxalate kidney stones is
still not clearly understood. In this field of studies, several new hypotheses are created, which
includes nucleation, reduction of nucleation, crystal growth and or aggregation of formation of
different crystals such as oxalate monohydrate and oxalate di-hydrate. The effect of some
urinary species such as ammonium oxalate, calcium, citrate, proteins and trace elements were
reported by the author. The kidney stone constituents along with trace minerals are grown in
silica gel medium (SMS) which provides the necessary growth simulation (in-vivo). In the
artificial urinary stone growth process, growth parameters within the different chemical
environments were carried out and reported for several urinary crystals such as CaHP, SrHP,
SrMHP, BaHP, BaMHP and MgHP. In the present investigation, BaSrCrMHP (Barium
Strontium Chromium Magnesium Hydrogen Phosphate) crystals are grown in different growth
faces to attain the total nucleation reduction. Extension of this investigation, many
characterization studies have been carried out and compared with reported results.