TITLE:
Nucleation Reduction Strategy of (Brushite) CHP Crystals in SMS Media and Its Characterization Studies
AUTHORS:
G. Kanchana, P. Sundaramoorthi, R. Santhi, S. Kalainathan, G.P. Jeyanthi
KEYWORDS:
Renal stones, MHP, calculi, surface morphology, growth parameters, trace elements, SDP, AMHP, Brushite.
JOURNAL NAME:
Journal of Minerals and Materials Characterization and Engineering,
Vol.7 No.1,
March
20,
2008
ABSTRACT: Kidney stone consist of various organic, inorganic and semi organic compounds.
Mineral oxalate monohydrate and di-hydrate is the main inorganic constituent of kidney
stones. However, the mechanisms for the formation of calcium oxalate kidney stone are
not clearly understood. In this field of study there are several hypothesis including
nucleation, crystal growth and or aggregation of formation of COMH, AOMH
(Ammonium oxalate monohydrate), CODH, and AODH (Ammonium oxalate di-hydrate)
crystals. The author has reported the effect of some urinary species such as ammonium
oxalates, calcium, citrate, proteins and trace mineral. The kidney stone constituents are
grown in the kidney environments, the silica gel medium (SMS) provides the necessary
growth simulation (in-vivo). In the artificial urinary stone preparation (growth) or
crystal growth, growth parameter identification with in the different chemical
environments is carried out. In the present study, CHP (calcium hydrogen phosphate)
crystals are grown in three different growth faces to attain the total nucleation
reductions. As an extension of this research, many characterization studies have been
carried out, and the results are compared and reported.