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Toescu, V., Nuttall, S.L., Martin, U., Nightingale, P., Kendall, M., Brydon, P. and Dunne, F. (2004) Changes in plasma lipids and markers of oxidative stress in normal pregnancy and pregnancies complicated by diabetes. Clinical Science, 106, 93-98. doi:10.1042/CS20030175

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• TITLE: Effect of sophrology on perinatal stress monitored by biopyrrin

  AUTHORS: Michiko Suzuki, Seiji Isonishi, Osamu Morimoto, Masahisa Ogawa, Kazuhiko Ochiai

  KEYWORDS: Biopyrrin; Oxidative Stress; Sophrology; Anesthesia

  JOURNAL NAME: Open Journal of Obstetrics and Gynecology, Vol.2 No.2, June 27, 2012

  ABSTRACT: Aim: Few stress markers are available for women in perinatal period. We introduced biopyrrin (BPn) for monitoring the perinatal stress and investigated how the stress could be regulated. Methods: Study patients consisted of 220 full-term pregnant women between 2006 and 2008. Cases were analyzed based on 1) pattern of delivery, the use of pain control (anesthesia) or hypnotics (Sophrology), 2) maternal complications, and 3) habitual smoking or alcohol consumption. Urinary samples were collected from pregnant women before and after delivery, and from newborn babies. Results: The average level of BPn in pregnant women was 2.61 ± 0.25 U/g·Creatinin (Cre). (Mean ± SE). This is significantly higher than age-matched non-pregnant women (0.79 ± 0.24 U/g·Cre). After normal delivery, BPn was significantly elevated to 5.29 ± 0.57 U/g·Cre (p