TITLE:
A comparative, randomized study of levonorgestrel Intrauterine System (LNG-IUS) vs Copper T 380 A intrauterine device applied during cesarean section
AUTHORS:
José A. López-Farfan, Alicia Hernandez-Gonzalez, Irvin J. Vélez-Machorro, Leopoldo A. Vázquez-Estrada
KEYWORDS:
Levonorgestrel-Releasing Intrauterine System; Medicated IUD; Copper T IUD; Cesarean Section; Postpartum Contraception; Ferritin Levels
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.2 No.2,
June
27,
2012
ABSTRACT: Objective: To assess levonorgestrel-releasing intrauterine system LNG-IUS (Mirena?) application at caesarean section (CS). Design: Randomized, comparative study. Setting: Department of obstetrics and gynecology in a primary reference hospital at Puebla City, Mexico. Sample: 396 women requiring CS signed informed consent and were randomly allocated to the post-placental application of LNG-IUS (198) or Copper T 380 A (198). Methods: Follow up visits at 6 weeks, and 6 and 12 months were performed. Main Outcomes Measures: IUDs expulsion, maternal and babies’ health conditions, breastfeeding and menstrual patterns, adverse effects and pregnancies. Differences between groups were analyzed by Fisher and X2 tests, Odds ratios, relative risk and 95% confidence limits, as appropriate. Results: After one year of follow up, no pregnancies were reported. The IUD expulsion rate was 4.5% in each group. LNG-IUS users had a higher incidence of amenorrhea (OR 2.5 95% CI 2.2 - 3) and menstrual patterns significantly brief and lighter than Copper T 380 A (p