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Ryan, H, Lilien, H and Bruce, R. (2003) Probabilistic disease classification of expression-dependent proteomic data from mass spectrometry of human serum. Journal of Computational Biology, 10, 925-946. doi:/10.1089/106652703322756159

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• TITLE: A computer aided detection framework for mammographic images using fisher linear discriminant and nearest neighbor classifier

  AUTHORS: Memuna Sarfraz, Fadi Abu-Amara, Ikhlas Abdel-Qader

  KEYWORDS: Principal Component Analysis; Fisher Linear Discriminant; Nearest Neighbor Classifier

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.5 No.6, June 15, 2012

  ABSTRACT: Today, mammography is the best method for early detection of breast cancer. Radiologists failed to detect evident cancerous signs in approximately 20% of false negative mammograms. False negatives have been identified as the inability of the radiologist to detect the abnormalities due to several reasons such as poor image quality, image noise, or eye fatigue. This paper presents a framework for a computer aided detection system that integrates Principal Component Analysis (PCA), Fisher Linear Discriminant (FLD), and Nearest Neighbor Classifier (KNN) algorithms for the detection of abnormalities in mammograms. Using normal and abnormal mammograms from the MIAS database, the integrated algorithm achieved 93.06% classification accuracy. Also in this paper, we present an analysis of the integrated algorithm’s parameters and suggest selection criteria.