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Kowalski, R.G., Claassen, J., Kreiter, K.T., Bates, J.E., Ostapkovich, N.D., Connolly, E.S. and Mayer, S.A. (2004) Initial misdiagnosis and outcome after subarachnoid hemorrhage. The Journal of the American Medical Association (JAMA), 291, 866-869. doi:10.1001/jama.291.7.866

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• TITLE: Acute headache in general neurology of China: Cause changes and predictors of short-term outcome

  AUTHORS: Guangsheng Wang, Yeting Zhou, Xiaodong Chen, Hongjian Wang, Tonghui Yang, Chunhong Chang, Yuanwei Wang, Hanpei Gu, Daoming Tong

  KEYWORDS: Acute Headache; Causes; Cerebrovescular Events; Subarachnoid Hemorrhage; Outcome

  JOURNAL NAME: World Journal of Neuroscience, Vol.2 No.2, May 29, 2012

  ABSTRACT: Background: Although patients with acute headache frequently present in emergency department, the causes and predictors of short-term outcome in patients with acute headache in general neurology have not been adequately investigated. Methods: We prospectively reviewed the medical records of 130 hospitalized acute headache pa-tients in general neurology of China. Their initial CT scan was assessed, as was their lumbar puncture (LP) examination if performed. Results: The main cause of acute headache was acute secondary headache (80.8%), which was mainly attributable to acute cerebrovascular events (72.4%) followed by intracranial infection (19.0%). Among the 10.8% of patients who died during hospitalization most (85.7%) had subarachnoid hemorrhage (SAH). Significant predictors of survival were severe headache versus thunderclap headache, meningismus, de-layed loss of consciousness, and hypertension (all p