TITLE:
The effect of age, gender, level of adiposity and diabetes duration on glycated hemoglobin reduction after anti-diabetic therapy in type-2 diabetic patients
AUTHORS:
Chinwe O. Ewenighi, Uchechukwu Dimkpa, Babatunde I. Adejumo, Joel C. Onyeanusi, Isaac N. Nnatuanya, Uzor Simon, Linus U. M. Onoh, Uchechukwu Ezeugwu
KEYWORDS:
Glycated Hemoglobin; Age; Gender; Adiposity; Metformin; Diet
JOURNAL NAME:
Journal of Diabetes Mellitus,
Vol.2 No.2,
May
25,
2012
ABSTRACT: Background: It is established that glycemic control measures involving diet and oral medication reduce glycated hemoglobin concentration (HbA1c) in type-2 diabetic patients. Aim: We aimed to determine whether HbA1c reduction after diabetic treatment is affected by age, gender, level of adiposity and diabetes duration in type-2 diabetic patients. Methods: One hundred and four type-2 diabetic patients participated in a 20-week diabetic control therapy involving oral medication (metformin) and lifestyle intervention (diet). We compared the HbA1c reduction after treatment between the elderly and non-elderly; males and females; overweight/obese and non-overweight/obese; and long-standing and newly diagnosed patients. Results: After the treatment, participants had mean HbA1c reduction of 1.1 ± 1.31% and weight loss of 2.46 ± 1.79 kg. Forty-six (44.2%) of the patients had acceptable HbA1c level of p p p