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A. Mongae, J. A. Palop, A. Ochoa de Retana, I. Urbasos and A. E. Fernandez, “New Quinoxalines and Pyrazolo [3,4-b]quinoxalines with An-tihypertensive Activity,” Ana- les de Quimica, Serie C: Quimica Organica y Bioquimica, Vol. 84, No. 3, 1988, pp. 364-366.

has been cited by the following article:

• TITLE: Aspects on the Mechanism of the 1-Phenyl-1H-pyrazolo[3,4-b]quinoxaline Formation

  AUTHORS: Mohamed A. Mostafa, Salah L. Aboulela, Mohammed A. E. Sallam, Farida F. Louis, Thorleif Anthonsen

  KEYWORDS: 2-(D-arabino-tetritol-1-yl)quinoxaline; Pyrazolo[3, 4-b]quinoxalines; 3-(D-erythro-glycerol-1-yl)-1-phenyl-1H-pyrazolo-[3, 4-b]qunoxaline; 4, 5-Dichloro-o-phenylenediamine; 6, 7-Dichloro-2-(D-arabino-tetritol-1-yl)quinoxaline; 6, 7-Dichloro-3-(D-erythro-glycerol-1-yl)-1-phenyl-1H-pyrazolo-[3, 4-b]quinoxaline; N, N-Benzylphenylhydrazine hydrochloride

  JOURNAL NAME: Green and Sustainable Chemistry, Vol.2 No.2, May 11, 2012

  ABSTRACT: Condensation of D-glucose, o-phenylenediamine and N,N-benzylphenylhydrazine hydrochloride (NNBPHH) in a one-pot reaction, or condensation of 2-(D-arabino-tetritol-1-yl) quinoxaline and NNBPHH, gave 3-(D-erythro-glycerol-1- yl)-1-phenyl-1H-pyrazolo[3,4-b]quinoxaline. The structure of the latter was determined by 1H NMR spectroscopy and by synthesis using phenylhydrazine hydrochloride instead of NNBPHH. Condensation of D-glucose and 4,5-dichloro-o-phenylenediamine gave 6,7-dichloro-2-(D-arabino-tetritol-1-yl)quinoxaline, which upon condensation with NNBPHH gave the corresponding 6,7-dichloro-3-(D-erythro-glycerol-1-yl)-1-phenyl-1H-pyrazolo[3,4-b]quinoxaline. The structure and mechanism of formation of these compounds are discussed.