TITLE:
Endometrial Cancer in Libreville: A Six-Year Retrospective Study (2020-2025)
AUTHORS:
Mve Robert Eya’ama, Obiang Pamphile Assoumou, Edou Siddi Gerard Mba, Anouchka Mewie, Mve Ngou Kévin Ngou, Ondo Cyrielle Mbang, Mvono Iréné Edzo, Ntoutoume Elsa Nzame, Ntamack Jacques Albert Bang, Jean François Meye
KEYWORDS:
Endometrial Cancer, Advanced-Stage and Aggressive Disease, Gabon
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.16 No.11,
November
11,
2026
ABSTRACT: Introduction: Endometrial cancer is a gynaecological malignancy with a rising incidence. The objective was to describe the epidemiological, diagnostic and therapeutic features of endometrial cancer at the Fondation Jeanne Ebori Mother and Child Teaching Hospital. Patients and Methods: A retrospective descriptive study was conducted over 6 years (January 2020 to December 2025), including patients with a histologically confirmed diagnosis of endometrial cancer. Results: Thirty-three cases were identified, accounting for 7.1% (33/463) of all gynaecological and breast malignancies. Postmenopausal women accounted for 93.9% (n = 31) of cases. The main presenting symptom was postmenopausal bleeding, reported in 31 patients (93.9%). Endometrioid adenocarcinoma was the predominant histological type, in 75.8% (n = 25) of cases. Among these, Grade 3 tumours accounted for 64.0% (n = 16) of cases. Advanced-stage disease (FIGO III-IV) was found in 18 patients (54.5%). Surgery was performed in 12 patients (36.4%), while 16 (48.5%) received chemotherapy, given with palliative intent in 68.8% (n = 11) of cases. Conclusion: Endometrial cancer is characterised by a high proportion of advanced-stage and aggressive disease, underlining the need for earlier diagnosis and for strengthened multidisciplinary management.